Metabolic Alkalosis on the NCLEX

Causes (vomiting, diuretics), saline-responsive vs not.

Metabolic alkalosis is high pH from non-respiratory cause.

ABG pattern

pH >7.45, HCO3 >26.

Causes

Vomiting (loss of HCl), NG suctioning, diuretics, hyperaldosteronism, severe hypokalemia, milk-alkali.

Treatment

Saline (most causes are saline-responsive, volume depleted). Replace K+ and Cl-. Treat underlying.

Frequently asked

Hyperaldosteronism, saline responsive?

No. Need to treat aldosterone excess.

Vomiting and metabolic alkalosis?

Loss of H+. Volume depletion drives kidney to retain HCO3.

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