Anemias Overview: NCLEX Priorities

Iron-deficiency, B12, folate, sickle cell, quick patterns and treatments.

Anemia patterns the NCLEX tests. Each has a signature.

Iron-deficiency anemia

Microcytic, hypochromic. Causes: blood loss, poor intake, pregnancy. Iron supplementation oral (ferrous sulfate) or IV. Take with vitamin C; avoid with calcium/PPI. Black stools normal.

B12 deficiency

Macrocytic, neuro symptoms (paresthesias, ataxia). Causes: pernicious anemia (intrinsic factor deficiency), vegan diet, gastric surgery, ileal disease. B12 IM or sublingual.

Folate deficiency

Macrocytic, no neuro symptoms. Causes: poor intake, alcohol, methotrexate. Folate supplementation. Distinguish from B12, giving folate alone in B12 deficiency can worsen neuro damage.

Sickle cell

Hemoglobin S → sickling under stress. Vaso-occlusive crisis: pain, hydration, opioids, O2 if hypoxic, treat infection. Hydroxyurea reduces crisis frequency.

Frequently asked

Why blood transfusion in anemia?

Hgb <7 generally (<8 in cardiac disease). Symptomatic anemia.

Iron with food?

Better absorbed empty stomach. Take with food only if GI upset.

Quick check

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