Cirrhosis: NCLEX Priorities

Cirrhosis: ascites, varices, encephalopathy, lactulose, paracentesis.

Cirrhosis is end-stage liver scarring. NCLEX tests complications: ascites, varices, encephalopathy.

Causes

Alcohol, hepatitis B/C, NAFLD, autoimmune, hemochromatosis.

Ascites

Sodium restriction (<2 g/day), diuretics (spironolactone + furosemide), paracentesis for tension. Albumin replacement after large-volume paracentesis.

Varices

Esophageal varices → upper GI bleed risk. Non-selective beta-blockers (propranolol, nadolol) for prevention. Band ligation prophylactic in large varices. Active bleed: octreotide + endoscopy + antibiotics + transfusion.

Encephalopathy

Ammonia accumulation. Lactulose (titrate to 2-3 soft stools/day), traps ammonia. Rifaximin added in recurrent. Treat precipitants (infection, GI bleed, dehydration).

Hepatorenal, hepatopulmonary, SBP

Multiple end-organ complications. SBP (spontaneous bacterial peritonitis) treated with ceftriaxone + albumin.

Frequently asked

Why albumin after paracentesis?

Prevents post-paracentesis circulatory dysfunction. >5L drained: give albumin.

Lactulose taste, patient won't take?

Can give via NG or rectally if needed. Often becomes essential.

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