-azole: Antifungals (Drug Ending Cheat Sheet)

If the drug ends in -azole, it's typically an antifungal.

Antifungals (and a few exceptions) end in -azole. Inhibit fungal cell membrane synthesis.

Common examples

Fluconazole, itraconazole, voriconazole, ketoconazole.

Note exceptions

-prazole = PPI (omeprazole, pantoprazole), not antifungal. Be careful with the ending.

Side effects

CYP450 interactions, hepatotoxicity.

Frequently asked

How to remember -azole vs -prazole?

PPIs are -prazole specifically (with the pr). Antifungals are -conazole / -azole only.

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