Lymphomas: NCLEX Priorities
Hodgkin vs non-Hodgkin: Reed-Sternberg, staging, treatment patterns.
Lymphomas are heterogeneous. NCLEX tests Hodgkin's Reed-Sternberg and the B symptoms.
Hodgkin's
Reed-Sternberg cells on biopsy. Young adults peak (and elderly). Highly curable. Chemo (ABVD) + radiation.
Non-Hodgkin's
Heterogeneous group. DLBCL most common aggressive type (R-CHOP curable in many). Follicular indolent.
B symptoms
Fever, drenching night sweats, weight loss >10%. Worse prognosis when present.
Frequently asked
Lymphadenopathy workup?
Biopsy. Don't aspirate, need architecture.
Late effects of treatment?
Second cancers, cardiomyopathy (anthracyclines), pulmonary toxicity (bleomycin).
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