Multiple Sclerosis: NCLEX Priorities
MS: relapsing-remitting, fatigue, heat sensitivity, DMTs.
Multiple sclerosis is demyelinating. NCLEX tests symptom patterns and lifestyle teaching.
Recognition
Relapsing-remitting most common type. Symptoms vary by lesion location: optic neuritis, paresthesias, weakness, ataxia, bladder dysfunction, cognitive changes.
Heat sensitivity (Uhthoff's)
Heat worsens symptoms. Counsel: cool environment, avoid hot baths, swim in cool water.
Fatigue
Most common disabling symptom. Energy conservation. Amantadine or modafinil sometimes prescribed.
DMTs (disease-modifying therapies)
Interferons, glatiramer, fingolimod, ocrelizumab, natalizumab, others. Goal: reduce relapses and progression.
Acute exacerbation
IV methylprednisolone high-dose. Plasma exchange for refractory.
Frequently asked
Pregnancy and MS?
Often improves during pregnancy. Risk of postpartum flare. DMT selection adjusted.
Lhermitte's sign?
Electric-shock sensation down spine with neck flexion. Common in MS.
Quick check
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