PT/INR on the NCLEX
PT/INR: warfarin monitoring, target ranges, reversal.
PT/INR measures extrinsic and common pathways. Standardized as INR for warfarin monitoring.
Normal
INR ~1.0 (without anticoagulation).
Warfarin targets
INR 2-3 most indications. 2.5-3.5 mechanical valves.
Elevated INR
Hold warfarin. Vitamin K for moderate elevation (5-10 mg). FFP or PCC for active bleeding or very high INR.
Liver disease
Elevated PT/INR reflects synthetic dysfunction. Not 'fixable' with vitamin K usually.
Frequently asked
INR 8 with no bleeding, give vitamin K?
Yes, oral vitamin K reasonable. Hold warfarin.
Pre-op INR target?
<1.5 for most surgeries.
Quick check
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